Super Eagles stars Efe Ambrose and John Ogu will battle for one UEFA Champions League slot after Celtic and Hapoel Be'er Sheva were drawn against each other in the playoffs on Friday.
Ambrose's Celtic, who saw off Astana in the third qualifying round, face a stiff test in the playoffs against Ogu's debuting Hapoel, who defeated Olympiacos in the previous round.
Another Nigerian star involved in the playoffs, Kelechi Iheanacho, will face Steau Bucharest with his Manchester City side for a place in the group phase.
Monaco, who left out Elderson Echiejile in their third qualifying round victory over Fenerbahce, will battle Villarreal.
The first legs will be played on on 16, 17 August with the return legs the following week.
Play-off draw (16/17 & 23/24 August)
Steaua București (ROU) v Manchester City (ENG)
Porto (POR) v Roma (ITA)
Ajax (NED) v Rostov (RUS)
Young Boys (SUI) v Borussia Mönchengladbach (GER)
Villarreal (ESP) v Monaco (FRA)
Ludogorets Razgrad (BUL) v Viktoria Plzeň (CZE)
Celtic (SCO) v Hapoel Beer-Sheva (ISR)
FC København (DEN) v APOEL (CYP)
Dundalk (IRL) v Legia Warszawa (POL)
Dinamo Zagreb (CRO) v Salzburg (AUT)