Oxford remain without Marcus Browne and Jamie Mackie for the visit of holders Manchester City in the Carabao Cup. Midfielder Browne has a knee problem while forward Mackie could be sidelined for up to six weeks with a hip injury.
The third-round tie will also come too soon for Samir Carruthers and Simon Eastwood while Rob Hall (knee) is a long-term absentee.
Oxford are struggling in League One after losing six of their nine matches.
City are set to make a raft of changes to the side that thrashed Cardiff in the Premier League at the weekend.
Brazilian defender Danilo could make his first appearance of the season, having been sidelined since injuring his ankle at the World Cup, while fringe first-teamers Oleksandr Zinchenko and Brahim Diaz are set to be involved.
Nicolas Otamendi and Riyad Mahrez, who scored his first goals for City in Saturday’s 5-0 win, may feature.
Pep Guardiola is weighing up whether to hand a City debut to teenage goalkeeper Arijanet Muric.