Mark Hughes has been sacked as Southampton manager after 10 matches without a victory in the Premier League.
Assistant manager Mark Bowen and assistant coach Eddie Niedzwiecki have also left the club with immediate effect.
A Southampton club statement read: “We would like to express our thanks to Mark and his staff for all of their efforts during their time at St Mary’s.
“The search for a new manager to take the club forward is already under way.”
Hughes was appointed as Southampton manager in March on an initial deal until the end of last season but after maintaining the club’s Premier League status was rewarded with a three-year deal in May.
In his eight months in charge the 55-year-old managed only five victories in his 27 games in charge and Southampton will now begin their search for a fourth manager in just over two years.
Assistant coach Kelvin Davis will lead the team for Wednesday’s Premier League game against Tottenham at Wembley and will hold a news conference today at 2pm at the club’s training ground.